Am I Depressed or Just Sad? Understanding Depression Symptoms and Brain-Based Strategies to Resolve Chronic Sadness

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Man suffering from unknown depression symptoms with partner, contemplating if he's depressed or just sad, considering brain-based treatment for depression

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What’s the Difference Between Sadness and Depression?

Depression symptoms are about being sad, sure—but it’s more than that. Clinical depression is a mental health condition involving a constellation of symptoms that go beyond sadness. These symptoms include feeling exhausted, losing interest in activities you usually enjoy, experiencing significant changes in appetite or weight, having trouble sleeping or sleeping too much, feeling worthless or excessively guilty, having difficulty thinking or concentrating, or even having recurrent thoughts of death and suicide.

Episodes of depression last at least two weeks at a time, often much longer, and a sad event can trigger them, or they can seemingly come out of nowhere. It’s also important to note that depression can manifest differently in different people. Some might experience more physical symptoms like headaches or stomach problems, while others might experience more emotional symptoms like persistent sadness or irritability.

How Do I Know If I’m Sad or Depressed?

If you’re sad because you lost your job, are going through a breakup, or lost someone in your life… it’s certainly no fun, but it’s also pretty normal. Sadness, even extreme sadness, is a natural reaction to events like these. That said, regular sadness can also turn into depression. If the feelings don’t get better over time, or if your mood starts to get in the way of your daily life, you might develop depression.

For instance, if you find that your sadness is making it hard to get out of bed, go to work, or maintain your relationships, it might be more than just sadness. If you’re losing interest in things you used to enjoy, like hobbies or spending time with friends, that could also be a sign of depression.

Physical changes can also affect your mood. Some examples include hormone changes due to puberty or menopause or certain medical sessions or conditions. If you think you might be depressed, having a doctor review any medications you’re taking and test your thyroid and other hormone levels is a good idea. This is because certain medical conditions and medications can cause symptoms similar to depression, so it’s important to rule these out.

“Pain is inevitable. Suffering is optional.”

Dr. Sydney Ceruto, Founder MindLAB Neuroscience

The Promise of Brain-Based Therapy for Depression

When combined with brain-based counseling therapies, neuroscience advancements help us understand how and why people change. The foundation for brain-based therapy comprises neuroscience, attachment theory, and evidence-based approaches. This new therapy model identifies the most relevant aspects of theoretical psychology and those that may be counter-productive.

In brain-based therapy, the therapeutic process provides a way to rewire the brain to affect mood and behavior change. Trained professionals find the root of the problem and, with a combination of developing the therapeutic relationship and providing effective therapeutic modalities, modify the mental model so that it is stored in a more adaptive way.

One of the beautiful things about brain-based counseling is that the outcome is measurable. Furthermore, brain-based therapies encompass neuroscience, providing a more rapid and long-lasting result than the same issues addressed with talk therapy alone. Brain-based counseling is one of the most researched and effective methods to create this outcome. This therapy helps eliminate (as opposed to reducing) symptoms of not just depression but trauma and anxiety, among other conditions. This modality is also fast becoming an option for conditions that are difficult to address with other approaches.

Your therapy should be a transformative experience! A strong therapeutic relationship, clearly defined goals, and brain-based therapeutic modalities can help you get the best outcomes from your counseling and get you back into living your best life. At the conclusion of neuroscientific brain-based therapy, the goal is for each client to see and feel a measurable difference in their mood.

If you’re asking yourself, “Am I depressed or just sad?” and you’re interested in exploring brain-based therapy for depression, consider scheduling a consultation with me, Dr. Sydney Ceruto, Founder of MindLAB Neuroscience. Let’s work together to understand your depression symptoms you might not know and explore the promise of brain-based therapy to abolish your depression or chronic sadness.

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Dr. Sydney Ceruto

Founder & CEO of MindLAB Neuroscience, Dr. Sydney Ceruto is author of THE DOPAMINE CODE: How to Rewire Your Brain for Happiness and Productivity (Simon & Schuster, June 2026). She has pioneered Real-Time Neuroplasticity™—a proprietary protocol delivering precision performance engineering for high-performing executives, entrepreneurs, and elite professionals globally.

Through her proprietary methodologies—including NeuroConcierge™ and NeuroSync™—Dr. Ceruto provides neurological re-engineering that permanently optimizes neural pathways, eliminates behavioral limiting patterns, and sustains clarity and dominance under pressure. Her clients experience a 40% average increase in decision-making speed and hold a 4.9-star satisfaction rating across 316+ verified reviews.

Dr. Ceruto holds dual PhDs in Behavioral & Cognitive Neuroscience (NYU) and dual Master's degrees in Clinical Psychology and Business Psychology (Yale University).

Her work has transformed hundreds of clients across the globe, from corporate leaders and tech innovators to professional athletes and discerning families navigating complex life transitions. She is a 2024 Lifetime Achievement Award recipient from the World Coaching Congress, an inductee of Marquis Who's Who in America, and an Executive Contributor to Forbes Coaching Council since 2019.

Regularly featured in Forbes, USA Today, Newsweek, The Huffington Post, Business Insider, Fox Business, and CBS News. For media requests, visit our Media Hub.

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