OCD worsens because each compulsion rewires the CSTC loop through Hebbian co-firing, shifting it from ventral to dorsal striatum. See...
Read article : Why OCD Gets Worse Over Time: The Neural EscalationIntrusive Thought Patterns
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In OCD the orbitofrontal cortex overvalues threat, tagging ordinary thoughts as catastrophic. See how lateral OFC hyperactivity drives the compulsion...
Read article : Orbitofrontal Cortex and OCD: The Overvaluation LoopSSRIs help only 40 to 70 percent of people with OCD. The reason is a multi-circuit CSTC pattern, not low...
Read article : OCD and Serotonin Imbalance: Why SSRIs Fail for HalfOCD is driven by a glutamate excitatory imbalance, not a willpower problem. See how cortico-striatal loops misfire, and how the...
Read article : Glutamate and OCD: The Excitatory Imbalance in the BrainFighting intrusive thoughts makes them louder. Dr. Sydney Ceruto explains the ironic-process trap, the hippocampal GABA shortage, and the salience...
Read article : Why Suppressing Intrusive Thoughts Backfires | MindLAB NeuroscienceWhy won't your brain stop signaling something is wrong? Dr. Sydney Ceruto explains the rostral ACC error-monitor circuit driving OCD...
Read article : OCD Error Detection Brain | MindLAB NeuroscienceOCD and basal ganglia: how the brain's thought filter fails, why intrusive thoughts pass through the gate, and what restores...
Read article : OCD and Basal Ganglia | Dr. Sydney Ceruto — MindLAB